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The Impact of High-Frequency-Based Stability on the Onset of Action Potentials in Neuron Models
This paper studies the phenomenon of conduction block in model neurons using high-frequency biphasic stimulation (HFBS). The focus is …
Eduardo Cerpa
,
Nathaly Corrales
,
Matias Courdurier
,
Leo Medina
,
Esteban Paduro
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DOI
URL
Towards a more accurate quasi-static approximation of the electric potential for neurostimulation with kilohertz-frequency sources*
Objective. Our goal was to determine the conditions for which a more precise calculation of the electric potential than the …
Thomas Caussade
,
Esteban Paduro
,
Matias Courdurier
,
Eduardo Cerpa
,
Warren M. Grill
,
Leo Medina
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DOI
URL
Approximation and stability results for the parabolic FitzHugh-Nagumo system with combined rapidly oscillating sources
Eduardo Cerpa
,
Matias Courdurier
,
Esteban Hernández
,
Leo Medina
,
Esteban Paduro
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Project
DOI
An automatic method for detection of evoked events in the brain during spinal cord stimulation
Parkinson’s disease (PD) is a neurodegenerative brain disorder that mainly affects the elderly population and currently has no cure, …
Nicolás Vásquez
,
Mario Cáceres
,
Rómulo Fuentes
,
Leo Medina
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DOI
A partially averaged system to model neuron responses to interferential current stimulation
The interferential current (IFC) therapy is a noninvasive electrical neurostimulation technique intended to activate deep neurons using …
Eduardo Cerpa
,
Matias Courdurier
,
Esteban Hernández
,
Leo Medina
,
Esteban Paduro
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DOI
URL
Multiscale Entropy Analysis of Retinal Signals Reveals Reduced Complexity in a Mouse Model of Alzheimer's Disease
Alzheimer’s disease (AD) is one of the most significant health challenges of our time, affecting a growing number of the elderly …
Joaquín Araya-Arriagada
,
Sebastián Garay
,
Cristóbal Rojas
,
Claudia Duran-Aniotz
,
Adrian Palacios
,
Max Chacón
,
Leo Medina
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DOI
Design of a low-cost neuromuscular blockade monitoring device
The increasing number of hospitalizations due to the ongoing pandemic has brought medical devices to the forefront of clinical …
Leo Medina
,
Manuel Villalobos-Cid
,
Arturo Álvarez
,
Pedro Chaná-Cuevas
PDF
DOI
Creating a neuroprosthesis for active tactile exploration of textures
Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, …
Joseph E. O'Doherty
,
Solaiman Shokur
,
Leo Medina
,
Mikhail A. Lebedev
,
Miguel A. L. Nicolelis
PDF
DOI
Nerve excitation using an amplitude-modulated signal with kilohertz-frequency carrier and non-zero offset
BACKGROUND Incorporating kilohertz-frequency signals in transcutaneous electrical stimulation has been proposed as a means to overcome …
Leo Medina
,
Warren M. Grill
PDF
DOI
Quantitative Analysis of Kilohertz-Frequency Neurostimulation
Mainstream electrical stimulation therapies, e.g., spinal cord stimulation (SCS) and deep brain stimulation, use pulse trains that are …
Leo Medina
PDF
Quantification of Dorsal Column Fiber Responses in a Model of Kilohertz-Frequency Spinal Cord Stimulation
Introduction Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons …
Leo Medina
,
Nathan D. Crosby
,
John J. Janik
,
Warren M. Grill
Effects of frequency-dependent membrane capacitance on neural excitability
Objective. Models of excitable cells consider the membrane specific capacitance as a ubiquitous and constant parameter. However, …
Bryan Howell
,
Leo Medina
,
Warren M. Grill
PDF
DOI
Phantom Model of Transcutaneous Electrical Stimulation with Kilohertz Signals
textcopyright 2015 IEEE. Transcutaneous electrical stimulation (TES) of nerve fibers may be optimized by overcoming the impedance of …
Leo Medina
,
Warren M. Grill
DOI
Mammalian Motor Nerve Fibers, Models of
Leo Medina
,
Warren M. Grill
PDF
DOI
Volume conductor model of transcutaneous electrical stimulation with kilohertz signals.
OBJECTIVE: Incorporating high-frequency components in transcutaneous electrical stimulation (TES) waveforms may make it possible to …
Leo Medina
,
Warren M. Grill
PDF
DOI
Circuit and volume conductor models of transcutaneous electrical stimulation
Electrical stimulation of peripheral nerves is a widespread technique for the treatment of neurological diseases and disorders. …
Leo Medina
,
Warren M. Grill
DOI
Stochastic Facilitation of Artificial Tactile Sensation in Primates
Artificial sensation via electrical or optical stimulation of brain sensory areas offers a promising treatment for sensory deficits. …
Leo Medina
,
Mikhail A. Lebedev
,
Joseph E. O'Doherty
,
Miguel A. L. Nicolelis
DOI
Ore grade estimation by feature selection and voting using boundary detection in digital image analysis
In mining, rock classification plays a crucial role at different stages of the extraction process ranging from the design of the mine …
Claudio A. Perez
,
Pablo A. Estévez
,
Pablo A. Vera
,
Luis E. Castillo
,
Carlos M. Aravena
,
Daniel A. Schulz
,
Leonel E. Medina
PDF
DOI
A critical experimental study of the classical tactile threshold theory.
The tactile sense is being used in a variety of applications involving tactile human-machine interfaces. In a significant number of …
Claudio A. Perez
,
José R. Donoso
,
Leo Medina
DOI
Coincidence-enhanced stochastic resonance: Experimental evidence challenges the psychophysical theory behind stochastic resonance
Stochastic resonance (SR) is the counterintuitive phenomenon in which noise enhances detection of sub-threshold stimuli. The SR …
Claudio A. Perez
,
Theodore E. Cohn
,
Leo Medina
,
José R. Donoso
DOI
Linear versus nonlinear neural modeling for 2-D pattern recognition
This paper compares the classification performance of linear-system- and neural-network-based models in handwritten-digit …
Claudio A. Perez
,
Guillermo D. Gonzalez
,
Leo Medina
,
Francisco J. Galdames
DOI
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